Tissue Chip Funding Information
2016 Funding Announcements
RFA-TR-16-006(link is external):
Tissue Chip Testing Centers: Validating Microphysiological Systems (U24)
- Tissue Chip Specifications (Excel - 21KB)
- Confidential Disclosure Agreement (PDF - 27KB)
- Collaborative Research Agreement (PDF - 110KB)
Budget Change FAQ:
Q: What happens if an applicant exceeds the budget cap stated in the FOA?
A: If an applicant proposes a budget that exceeds the DIRECT COST cap, NCATS administration will work with the applicant to adjust the budget and scope according to the number of awards made.
2014 Project Awards
In fiscal year 2014, NIH awarded(link is external) approximately $17 million to 11 institutions to support collaborative research studies over the next three years to refine existing 3-D human tissue chips and combine them into an integrated system.
2012 Project Awards
In fiscal year 2012, NIH awarded(link is external)11 two-year projects to support studies to develop 3-D cellular microsystems that represent a number of human organ systems. It also awarded eight two-year projects that will explore the potential of stem and progenitor cells to differentiate into multiple cell types that represent the cellular architecture within organ systems. NCATS contributed about $9 million for these awards; the NIH Common Fund provided about $4 million.
These studies were evaluated after two years to ensure milestones were met for a second, three-year award to integrate the models at the organ or systems level with DARPA- and NIH-funded investigators.
2011 Funding Announcements
- RFA-RM-11-022 (link is external)
: Integrated Microphysiological Systems for Drug Efficacy and Toxicity Testing in Human Health and Disease (UH2/UH3)
- RFA-RM-12-001 (link is external)
: Stem/Progenitor Cell-Derived Human Micro-Organs and -Tissues (U18)